How to setup and launch Simulation in Quartus Prime Pro 24.2

Simulation is not performed directly in Quartus. You use the included QuestaSim tool. You can have Quartus generate the files you need for simulation and then it passes over to Questsim for the actual sim. All documented here: https://www.intel.com/content/www/us/en/docs/programmable/683870/24-2/siemens-eda-questasim-simulator-support-43743.html