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You can only resolve it by understanding it.
'Nothing works' is too vague. If you said something like "Accesses to an Avalon-MM slave at address XXX from C code running on a NIOS II processor, causes the processor to lock-up (no communications) ..." that would be a little more specific.
If you have two clocks in the system, then I you must have clock-domain crossing logic in the system to ensure valid data transfers.
Have you tried simulating your design in Modelsim?
Cheers,
Dave
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Thank you for your reply
Sorry, since i don't explain the problem exactly. This the error message that appears on console
verifying 00040000 ( 0%)
verify failed between address 0x40000 and 0x4655f
leaving target processor paused also it appear a window that contain
problem occured downloading elf process failed. I don't try to use a modelsim, because i don't know how can i use with nios-eclipse.