criteria for choosing best BER value

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How do we determine a value as the best BER value considering many values obtained after running the auto sweep feature in transceiver toolkit. From my basic knowledge i understood that it must be as low as possible.But, there might be many more lower values below that BER value. So how to fix upon a value.

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In the transceiver toolkit, you can also specify a target BER and then run auto sweep. The sweep will stop when achieve the target. You can also set a tighter BER if you want more margin.