Active Serial Programming ISSUE EPCS16 EP4CE15

nnead, yes set your MSEL pins to L,H,L. You will have to do a hardware change, by physically connecting wires to those nodes (or just cutting the existing MSEL1 track and adding a wire to 3.3V). I recently had to do the same exercise on a BGA b/c i messed up the MSEL pins... not a fun exercise... Hopefully your pcb layout isn't too complicated to debug.