How to simulate a Cyclone V with USB interface?

What I have done:

on Modelsim 10.5b , build up dut bestbench, and run some testcases.

I may want to use OOP methodology.

What I like to know:

1. Yes, the designers used Qsys for design. How can I use Qsys to run simulation.
2. Nativelink is simple. But, I am using Modelsim do file as makefile. If I have a OOP

simulation file structure, I don'think I can use Nativelink as I may have monitor, scoreboard,

testbench, testcase, driver, etc. Am I right?

Thanks!