Fast & Large block data transfer over USB - DE1/DE2 ?

Sorry, I was not clear.

Yes I do use a LED, but had not thought of borrowing the Init_Done LED.

I just have a connector on Con_1, with a couple of LEDS. One is fed from, as you say, a 1 sec toggle driven from counters, and is a nice clear indicator that the fpga is loaded and running.

It loads and runs fine when loaded from the built-in Morphic USB connector via DS2232H pin B, using the FTDI DX call from AplX :

FTStatus ← FT_ProgramMorphICDevice Hndl FileName

I then wanted to test the USB Blaster was working, so tried loading the program that way.

I used JTAG mode - would that be correct for this method ?

It appears to load (Quartus reports OK, Init_Done LED goes on), but blinky LED stays off.

Any thoughts ?