Very Slow when simulation Cyclone V UniPHY funtional model

Are you logging all signals to the waveform database? You should try an experiment to see what the best possible performance would be if you logged no signals. Then you may need make tradeoffs in performance by selecting only a restricted set of signals to log.

Are you running interactively or in non-gui command line mode?

Depending on which edition of Modesim 10.2 you have, there may be other options for optimizing and profiling your design. You should look at the Modelsim User Guide.