Hello Gurus, Please am new in fpga devices. I own CoreEP4CE6 fpga board. Anytime I upload my program on it, it works fine but lose the program when power goes off. please is there a way to permanently keep the program on it?

In Quartus, click File->Convert Programming File. This tool will allow you to re-target your .sof file (which programs the FPGA) to a .pof file (which will program the flash memory). Once you've created the .pof file, just use it in the Programmer like you currently use the .sof.