Hi Mark,
Yes. 3D RAM is supported. In Text Editor, you may go to Insert Template -> SystemVerilog -> Full Designs -> RAMs and ROMS to check on 3D RAM template. Below attached one of the ram template (check pic).
The maximum memory bits supported is not larger than 2**31 (2147483648) bits. Also, the largest device memory bits only until 271810560 bits. >=64GB RAM memories I think you mean external memory.
Error(22123): Netlist error at mixed_width_ram.sv(27): ram 'ram' with size larger than 2**31 bits is not supported for blasting
Thanks,
Best Regards,
Sheng