Issues using ST-Avalon on Stratix 10 MX development Kit

I generate the example design and it compiles well, then I added the pin locations and I got the same error message (16400) then I permute RX and TX pin location and the design compile well. Is it correct to permute the TX and RX location ? in the example design of the board and in the documentation they didn't permute ... how PCIe would work if the TX became an RX and the RX a TX?

I also tried to permute the TX and RX in my original design, now I have only the Error(14566) and after