Hi,
If you have build board with the Cyclone V interfacing EPCQ128A with ASx4 mode, then you can still use ASx1 mode. There is no need for you to make any hardware changes on the board. The pin connections are not that different between ASx4 mode and ASx1 mode. If the board was originally built using EPCQ128A with ASx1 mode, then you cannot use ASx4 mode since the 2 data pins (DATA[3..2] pin) are not connected.
As mentioned before, try to change the configuration setting to Active Serialx1 mode in the Device and Pin option in the Quartus project design and recompile to get new .sof file. Generate a new .jic and program it into the flash device and monitor if the configuration still fail (CONF_DONE low) or successful (CONF_DONE high).
Regards,
Nooraini