You will be able to use both clkoutp & clkoutn as independent general purpose, single ended I/O.
Can I assume you want to drive clkoutp from the PLL?
Yes, you should be able to both drive clkoutp (as a single ended signal) from the PLL and use clkoutn as a general purpose I/O pin.
I've just tried this, successfully, albeit with a Cyclone IV part - I don't have Cyclone III installed. It will quite happily allow me to use clkoutn as an input or output signal whilst using clkoutp as a single ended PLL output signal.
Put a small project together and let Quartus give you the answer for Cyclone III.
Cheers,
Alex