Hi,
By I2C, do you mean I2C remote system update?
There is not direct replacement for EPM3064ATC44.
MAX 10 is the latest CPLD that you can use. All MAX 10 device can be use to implement I2C. You can refer to MAX 10 device overview to see which MAX 10 device is suitable for your programming.
https://www.intel.com/content/dam/www/programmable/us/en/pdfs/literature/hb/max-10/m10_overview.pdf (page 5)
You can also refer to I2C remote system update design example for more information on I2C.
https://fpgacloud.intel.com/devstore/platform/15.1.0/Standard/i2c-remote-system-update-example/
Regards,
Aiman