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Dividing the measured differential voltage on the new R53 resistor with its nominal value I obtain the current value (Idesign).
Idesign*1.2V=Ptotal_measured ! Am I right ? :D
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Yes.
Here's what I have done in the past;
1) Create a design with a block of control registers with control bits.
2) Route a control bit to a block of registers that can be enabled to toggle (50-percent duty cycle).
3) Write a Modelsim simulation to generate a .vcd file for various numbers of toggling registers enabled, and use Quartus to provide power estimates.
4) Download the design to the board, and enable various numbers of toggling registers, and measure the power.
5) Compare (3) and (4) to see how good the estimates are.
I think I saw an agreement within the 10% to 20% range.
Cheers,
Dave