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I'm having the same issue.
It's very weird, because the JTAG programmer works fine. I have tried two brand-new USB-Blaster IIs with this.
It's even weirder, because this morning SignalTap II was working, then I made a change to the design, and now it doesn't.
Another detail. In the SignalTap II GUI, in the JTAG Chain Configuration window, in the Hardware box I see my USB-BlasterII recognized. I can scan the JTAG chain, too, and it finds the FPGA (a Cyclone V). Attempting to program the device results in the "Invalid JTAG configuration" error. Now when I click the "Setup ..." box in the JTAG Chain Configuration, in the Hardware Settings tab for "currently selected hardware" I see "No Hardware" chosen. I pull that down and select the USB Blaster II and click close. Again, I try to program the device and get the same "Invalid JTAG configuration" error.
But back in the Programmer program (only one is open at a time), if I click the "Hardware Setup" button, the same hardware select dialog pops up as in SignalTap II, only this time "Currently selected hardware" is my USB-BlasterII," not "No Hardware."
So there is something screwy going on with how SignalTap II chooses the JTAG hardware.
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I uninstalled the drivers, downloaded the stand alone programmer, installed it as administrator, and cycled power. Now Signal Tap works.
I remember now that when I installed Orcad many jobs ago the installation instructions said to Install as Administrator.
Perhaps ALTERA should add that to its install instructions
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