How to process this warning of PLL?

Hi Dears,

In my design, i used PLL to generate pulses, which are less related with other clocks(come out from PLL). But when i generate by using PLL and get below critical warnings. Do i need to worry about them?

Critical Warning (15537): Implemented PLL "mypll_calin:inst1|altpll:altpll_component|pll" as Enhanced PLL type, but with critical warnings

Critical Warning (15526): PLL "mypll_calin:inst1|altpll:altpll_component|pll" has settings that may result in high compensation variability

Info (15099): Implementing clock multiplication of 419, clock division of 2100, and phase shift of 0 degrees (0 ps) for mypll_calin:inst1|altpll:altpll_component|_clk0 port