After compiling your program...
1. Connect PC USB to DE0-nano mini-USB
2. File / Open project...
3. File / Convert Programming Files
4. Click 'Open Conversion Setup Data...'
5. Select 'xxxx.cof' file
6. Click 'Generate' and close when done
7. Tools / Programmer
8. Click 'Hardware Setup...'
9. Select 'USB-Blaster', click 'Close'
10. Set 'Mode:' to 'JTAG'
11. Click 'Delete' to clear any files or devices
12. Select 'xxxx.jic' file from the 'output_files' directory
13. Check'Program/Configure' box
14. Click 'Start' to begin programming (takes a few minutes)
15. Unplug and replug the USB cable to cycle power (loads new configuration)
Note: No external power supply should be used when performing the above as it will conflict with USB supplied power.