Can EPCQ16ASI8N completely replace EPCS16SI8N?

I used EPCQ16ASI8N to replace EPCS16SI8N, but I found out that I can't burn the program.I found in the datasheet that the structure of EPCS16SI8N is AS × 1, EPCQ16ASI8N has AS × 1 and AS × 4.The orde...