Can PCIe Hard Core IP configured as gen3x8 interface, 256 bits, 256Mhz, with Avanlon-MM with DMA work on 10AS066N3F40E2SG?

Can PCIe Hard Core IP configured as gen3x8 interface, 256 bits, 256Mhz, with Avanlon-MM with DMA work on 10AS066N3F40E2SG? The TimeQuest showd a lot of timing violations within the IP, some of which ...