Thanks for the note!
Yes, there is another USB port in action. I will try to disconnect that and see if it helps. However, the problem seems to be in finding the inf file or the file itself is hosed.
Plugging in the USB Blaster pod brings up the "new hardware" window, so it seems to be functional.
I installed Quartus on my F: drive. I'm wondering if that is why it can't find anything. My C: drive is small, so I prefer to load software elsewhere.
I found a copy of the driver on my laptop where I also have Quartus running OK. The Blaster works OK there. I will try to copy this driver file (and the SYS files) when I get back. I saw that download link, but thought it was for a different stand alone programmer. It says nothing about using it for the USB Blaster.