Problem with Quartus Prime 16.0 Lite Edition.

So you need to be a lot more specific about your configuration. Like what O/S you are running on.

What family and device are you using. Be very specific.

Has the design compiled successfully before (ie, on another version of Quartus, or another system)? If so, what is it's device utilization?

The more info you can provide up front about your configuration the better answers you will get to help solve your problem.

Just saying:

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Can anyone help me with this issue? Whenever I start compiling my design in Quartus Prime 16.0 Lite Edition, the memory consumption shoots up to 100 % and Quartus becomes " Not Responding".

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gives others precious little info to go on and most folks will just pass on trying to answer your question.