Help: HSMC and I2C

I've recently resurrected this project after taking a needed break. Unfortunately my situation is similar.

I've been able to view the clock and data signals using a logic analyzer and their appears to be interference on the lines. For example, the data line will blip low at random intervals. This translates into incorrect bits being received on either end.

Could this be a problem with the pull up resistor not being large enough? Anyone had similar problems?

Thanks