Error(18210): LogicLock region assignments cannot be used in Quartus Prime Pro Edition. Remove these

Yes, as the error message stated, you will need to remove all Logic Lock assignments in your QSF file.

You may also visit this webpage to check the cause of Quartus error messages and the respective actions to resolve them.

Link: https://www.intel.com/content/www/us/en/programmable/quartushelp/current/index.htm#msgs/msgs/eqhd_invalid_region_assignment.htm

Regards,

Richard Tan