Simulation script generation in quartus II

Hello, have you had any success? I have seen this done from a Development Board from PLDA and the .tcl script was very long (200+ lines). The script had entries to compile every megafucntion within your design. One would open ModelSim and type "do plda_simulate.tcl" and it would compile the project and run the simulation testbench. I have been running the RTL simulation from Quartus->Tools->Run RTL Simulation Tool but now I'm having a problem with a project where ModelSim says, "Failed to open design unit file in read mode". Turns out that there is a file path error that Quartus generates that I'm unable to fix so I'm looking at doing what you are asking for help on.