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Sopc builder should have generated automatically a .sdc file for your system.
You must include it in your Quartus project.
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You have to enable the settings for that? Cauze i can't find it in the main
directory.
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Also make sure your checked the "Timing driven synthesis" in Analysis&Synthesis settings and follow the other guidelines reported by timing optimization advisor.
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I did.
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Final note: probably this is not your current problem, but usually you must drive the sdram clock pin with a phase lead relative to clock used by sopc system.
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Probably you need to apply that in the sdc aswell. How?