Setup Hold times for Cyclone IV Flops

I'm not sure if they're in the handbook or not. It probably is somewhat dependent on what input to the flop is used, i.e. data, clock enable, sync load, etc. In reality, these values are pretty useless by themselves, as the external delay differences between clock and data will be exponentially larger.(Are you asynchronously sampling data, and just trying to get an idea of how often it will go metastable? That's the only thing I can think of where these might be important).

In TimeQuest, when you do setup and hold analysis, you will see a uTsu and uTh parameter.

And the Tsu is not 2.5ns. It will probably be closer to 1/100th of that. That 2.5ns is how fast the clock tree can toggle and is independent of the FFs.