clock setup problems!

Tools -> Advisors -> Timing Optimization Advisors is a good starting place for switches in Quartus to help with timing. I would recommend that for a data path problem, but if you have a clock skew problem, the cause of the clock skew should be addressed first. You may be aware of what it is, determined that it has to be, and evaluated that there is no way to reduce the skew, but if not, I would do that first.